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p21(Waf1/Cip1) Inhibition of Cyclin E/Cdk2 Activity Prevents Endoreduplication after Mitotic Spindle Disruption
During a normal cell cycle, entry into S phase is dependent on completion of mitosis and subsequent activation of cyclin-dependent kinases (Cdks) in G(1). These events are monitored by checkpoint pathways. Recent studies and data presented herein show that after treatment with microtubule inhibitors...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC83879/ https://ncbi.nlm.nih.gov/pubmed/9858545 |
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