Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

Although activating mutations of the anaplastic lymphoma kinase (ALK) membrane receptor occur in ~10% of neuroblastoma (NB) tumors, the role of the wild-type (WT) receptor, which is aberrantly expressed in most non-mutated cases, is unclear. Both WT and mutant proteins undergo extracellular domain (...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Rep
Autori principali: Huang, Hao, Gont, Alexander, Kee, Lynn, Dries, Ruben, Pfeifer, Kathrin, Sharma, Bandana, Debruyne, David N., Harlow, Matthew, Sengupta, Satyaki, Guan, Jikui, Yeung, Caleb M., Wang, Wenchao, Hallberg, Bengt, Palmer, Ruth H., Irwin, Meredith S., George, Rani E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8328392/
https://ncbi.nlm.nih.gov/pubmed/34260934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109363
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi