ALK ligand ALKAL2 potentiates MYCN‐driven neuroblastoma in the absence of ALK mutation

High‐risk neuroblastoma (NB) is responsible for a disproportionate number of childhood deaths due to cancer. One indicator of high‐risk NB is amplification of the neural MYC (MYCN) oncogene, which is currently therapeutically intractable. Identification of anaplastic lymphoma kinase (ALK) as an NB o...

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Vydáno v:EMBO J
Hlavní autoři: Borenäs, Marcus, Umapathy, Ganesh, Lai, Wei‐Yun, Lind, Dan E, Witek, Barbara, Guan, Jikui, Mendoza‐Garcia, Patricia, Masudi, Tafheem, Claeys, Arne, Chuang, Tzu‐Po, El Wakil, Abeer, Arefin, Badrul, Fransson, Susanne, Koster, Jan, Johansson, Mathias, Gaarder, Jennie, Van den Eynden, Jimmy, Hallberg, Bengt, Palmer, Ruth H
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849294/
https://ncbi.nlm.nih.gov/pubmed/33411331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105784
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