ALK ligand ALKAL2 potentiates MYCN‐driven neuroblastoma in the absence of ALK mutation

High‐risk neuroblastoma (NB) is responsible for a disproportionate number of childhood deaths due to cancer. One indicator of high‐risk NB is amplification of the neural MYC (MYCN) oncogene, which is currently therapeutically intractable. Identification of anaplastic lymphoma kinase (ALK) as an NB o...

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Udgivet i:EMBO J
Main Authors: Borenäs, Marcus, Umapathy, Ganesh, Lai, Wei‐Yun, Lind, Dan E, Witek, Barbara, Guan, Jikui, Mendoza‐Garcia, Patricia, Masudi, Tafheem, Claeys, Arne, Chuang, Tzu‐Po, El Wakil, Abeer, Arefin, Badrul, Fransson, Susanne, Koster, Jan, Johansson, Mathias, Gaarder, Jennie, Van den Eynden, Jimmy, Hallberg, Bengt, Palmer, Ruth H
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849294/
https://ncbi.nlm.nih.gov/pubmed/33411331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105784
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