Targeted Disruption of ALK Reveals a Potential Role in Hypogonadotropic Hypogonadism

Mice lacking ALK activity have previously been reported to exhibit subtle behavioral phenotypes. In this study of ALK of loss of function mice we present data supporting a role for ALK in hypogonadotropic hypogonadism in male mice. We observed lower level of serum testosterone at P40 in ALK knock-ou...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Witek, Barbara, El Wakil, Abeer, Nord, Christoffer, Ahlgren, Ulf, Eriksson, Maria, Vernersson-Lindahl, Emma, Helland, Åslaug, Alexeyev, Oleg A., Hallberg, Bengt, Palmer, Ruth H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425494/
https://ncbi.nlm.nih.gov/pubmed/25955180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123542
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