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Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib

Tumors with anaplastic lymphoma kinase (ALK) fusion rearrangements, including non-small-cell lung cancer and anaplastic large cell lymphoma, are highly sensitive to ALK tyrosine kinase inhibitors (TKIs), underscoring the notion that such cancers are addicted to ALK activity. Although mutations in AL...

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Bibliografiset tiedot
Julkaisussa:Cold Spring Harb Mol Case Stud
Päätekijät: Guan, Jikui, Fransson, Susanne, Siaw, Joachim Tetteh, Treis, Diana, Van den Eynden, Jimmy, Chand, Damini, Umapathy, Ganesh, Ruuth, Kristina, Svenberg, Petter, Wessman, Sandra, Shamikh, Alia, Jacobsson, Hans, Gordon, Lena, Stenman, Jakob, Svensson, Pär-Johan, Hansson, Magnus, Larsson, Erik, Martinsson, Tommy, Palmer, Ruth H., Kogner, Per, Hallberg, Bengt
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071567/
https://ncbi.nlm.nih.gov/pubmed/29907598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a002550
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