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ALK ligand ALKAL2 potentiates MYCN‐driven neuroblastoma in the absence of ALK mutation

High‐risk neuroblastoma (NB) is responsible for a disproportionate number of childhood deaths due to cancer. One indicator of high‐risk NB is amplification of the neural MYC (MYCN) oncogene, which is currently therapeutically intractable. Identification of anaplastic lymphoma kinase (ALK) as an NB o...

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書誌詳細
出版年:EMBO J
主要な著者: Borenäs, Marcus, Umapathy, Ganesh, Lai, Wei‐Yun, Lind, Dan E, Witek, Barbara, Guan, Jikui, Mendoza‐Garcia, Patricia, Masudi, Tafheem, Claeys, Arne, Chuang, Tzu‐Po, El Wakil, Abeer, Arefin, Badrul, Fransson, Susanne, Koster, Jan, Johansson, Mathias, Gaarder, Jennie, Van den Eynden, Jimmy, Hallberg, Bengt, Palmer, Ruth H
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849294/
https://ncbi.nlm.nih.gov/pubmed/33411331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105784
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