Cerebral endothelial cell-derived small extracellular vesicles enhance neurovascular function and neurological recovery in rat acute ischemic stroke models of mechanical thrombectomy and embolic stroke treatment with tPA

Treatment of patients with cerebral large vessel occlusion with thrombectomy and tissue plasminogen activator (tPA) leads to incomplete reperfusion. Using rat models of embolic and transient middle cerebral artery occlusion (eMCAO and tMCAO), we investigated the effect on stroke outcomes of small ex...

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Bibliographic Details
Published in:J Cereb Blood Flow Metab
Main Authors: Li, Chao, Wang, Chunyang, Zhang, Yi, Alsrouji, Owais K, Chebl, Alex B, Ding, Guangliang, Jiang, Quan, Mayer, Stephan A, Lu, Mei, Kole, Max K, Marin, Horia L, Zhang, Li, Chopp, Michael, Zhang, Zheng Gang
Format: Artigo
Language:Inglês
Published: SAGE Publications 2021
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327102/
https://ncbi.nlm.nih.gov/pubmed/33557693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X21992980
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