Cerebral endothelial cell-derived small extracellular vesicles enhance neurovascular function and neurological recovery in rat acute ischemic stroke models of mechanical thrombectomy and embolic stroke treatment with tPA

Treatment of patients with cerebral large vessel occlusion with thrombectomy and tissue plasminogen activator (tPA) leads to incomplete reperfusion. Using rat models of embolic and transient middle cerebral artery occlusion (eMCAO and tMCAO), we investigated the effect on stroke outcomes of small ex...

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Dades bibliogràfiques
Publicat a:J Cereb Blood Flow Metab
Autors principals: Li, Chao, Wang, Chunyang, Zhang, Yi, Alsrouji, Owais K, Chebl, Alex B, Ding, Guangliang, Jiang, Quan, Mayer, Stephan A, Lu, Mei, Kole, Max K, Marin, Horia L, Zhang, Li, Chopp, Michael, Zhang, Zheng Gang
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2021
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327102/
https://ncbi.nlm.nih.gov/pubmed/33557693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X21992980
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