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Atorvastatin extends the therapeutic window for tPA to 6 h after the onset of embolic stroke in rats
We investigated the neuroprotective effect of atorvastatin in combination with delayed thrombolytic therapy in a rat model of embolic stroke. Rats subjected to embolic middle cerebral artery (MCA) occlusion were treated with atorvastatin at 4 h, followed by tissue plasminogen activator (tPA) at 6 or...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845317/ https://ncbi.nlm.nih.gov/pubmed/19638998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.105 |
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