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MRI evaluation of BBB disruption after adjuvant AcSDKP treatment of stroke with tPA in rat
The primary limitation of thrombolytic treatment of ischemic stroke with tPA is the hemorrhagic risk. We tested AcSDKP (N-acetyl-seryl-aspartyl-lysyl-proline), as an auxiliary therapeutic agent, to reduce blood-brain barrier (BBB) disruption in a combination tPA thrombolytic treatment of stroke. Wis...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4044825/ https://ncbi.nlm.nih.gov/pubmed/24769225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.04.025 |
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