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AcSDKP Regulates Cell Proliferation through the PI3KCA/Akt Signaling Pathway

The natural tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) is generated from the N-terminus of thymosin-β4 through enzymatic cleavage by prolyl oligopeptidase (POP). AcSDKP regulation of proliferation of different cells is implicated in hematopoiesis and angiogenesis. This tetrapeptide present in al...

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Detalhes bibliográficos
Main Authors: Hu, Ping, Li, Bin, Zhang, Wenhua, Li, Yijian, Li, Guang, Jiang, Xinnong, Wdzieczak-Bakala, Joanna, Liu, Jianmiao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820705/
https://ncbi.nlm.nih.gov/pubmed/24244481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079321
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