Chimeric human opsins as optogenetic light sensitisers

Human opsin-based photopigments have great potential as light-sensitisers, but their requirement for phototransduction cascade-specific second messenger proteins may restrict their functionality in non-native cell types. In this study, eight chimeric human opsins were generated consisting of a backb...

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Bibliografiske detaljer
Udgivet i:J Exp Biol
Main Authors: Hickey, Doron G., Davies, Wayne I. L., Hughes, Steven, Rodgers, Jessica, Thavanesan, Navamayooran, MacLaren, Robert E., Hankins, Mark W.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325934/
https://ncbi.nlm.nih.gov/pubmed/34151984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.240580
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