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Characterisation of light responses in the retina of mice lacking principle components of rod, cone and melanopsin phototransduction signalling pathways

Gnat(−/−), Cnga3(−/−), Opn4(−/−) triple knockout (TKO) mice lack essential components of phototransduction signalling pathways present in rods, cones and photosensitive retinal ganglion cells (pRGCs), and are therefore expected to lack all sensitivity to light. However, a number of studies have show...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hughes, Steven, Rodgers, Jessica, Hickey, Doron, Foster, Russell G., Peirson, Stuart N., Hankins, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908426/
https://ncbi.nlm.nih.gov/pubmed/27301998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28086
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