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Structures and implications of TBP–nucleosome complexes

The TATA box-binding protein (TBP) is highly conserved throughout eukaryotes and plays a central role in the assembly of the transcription preinitiation complex (PIC) at gene promoters. TBP binds and bends DNA, and directs adjacent binding of the transcription factors TFIIA and TFIIB for PIC assembl...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Wang, Haibo, Xiong, Le, Cramer, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325331/
https://ncbi.nlm.nih.gov/pubmed/34301908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2108859118
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