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Structures and implications of TBP–nucleosome complexes

The TATA box-binding protein (TBP) is highly conserved throughout eukaryotes and plays a central role in the assembly of the transcription preinitiation complex (PIC) at gene promoters. TBP binds and bends DNA, and directs adjacent binding of the transcription factors TFIIA and TFIIB for PIC assembl...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Wang, Haibo, Xiong, Le, Cramer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325331/
https://ncbi.nlm.nih.gov/pubmed/34301908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2108859118
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