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Accelerated expansion of pathogenic mitochondrial DNA heteroplasmies in Huntington’s disease
Mitochondrial dysfunction is found in the brain and peripheral tissues of patients diagnosed with Huntington’s disease (HD), an irreversible neurodegenerative disease of which aging is a major risk factor. Mitochondrial function is encoded by not only nuclear DNA but also DNA within mitochondria (mt...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8325154/ https://ncbi.nlm.nih.gov/pubmed/34301881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014610118 |
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