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Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals
A majority of mitochondrial DNA (mtDNA) mutations reported to be implicated in diseases are heteroplasmic, a status with coexisting mtDNA variants in a single cell. Quantifying the prevalence of mitochondrial heteroplasmy and its pathogenic effect in healthy individuals could further our understandi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4115537/ https://ncbi.nlm.nih.gov/pubmed/25002485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403521111 |
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