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Very Short Mitochondrial DNA Fragments and Heteroplasmy in Human Plasma

Cell free DNA (cfDNA) has received increasing attention and has been studied in a broad range of clinical conditions. However, few studies have focused on mitochondrial DNA (mtDNA) in the cell free form. We optimized DNA isolation and sequencing library preparation protocols to better retain short D...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zhang, Ruoyu, Nakahira, Kiichi, Guo, Xiaoxian, Choi, Augustine M.K., Gu, Zhenglong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095883/
https://ncbi.nlm.nih.gov/pubmed/27811968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36097
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