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Very Short Mitochondrial DNA Fragments and Heteroplasmy in Human Plasma

Cell free DNA (cfDNA) has received increasing attention and has been studied in a broad range of clinical conditions. However, few studies have focused on mitochondrial DNA (mtDNA) in the cell free form. We optimized DNA isolation and sequencing library preparation protocols to better retain short D...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Ruoyu, Nakahira, Kiichi, Guo, Xiaoxian, Choi, Augustine M.K., Gu, Zhenglong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095883/
https://ncbi.nlm.nih.gov/pubmed/27811968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36097
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