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Biosynthetic Proteases that Catalyze the Macrocyclization of Ribosomally Synthesized Linear Peptides
Circular peptides have long been sought after as scaffolds for drug design as they demonstrate protein-like properties in the context of small, constrained peptides. Traditional routes towards the production of cyclic peptides rely on synthesis or semi-synthetic methods, which restrict their use as...
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| Publicado en: | Biochemistry |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8324308/ https://ncbi.nlm.nih.gov/pubmed/29553721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00114 |
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