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Circular logic: Nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst
[Image: see text] A protease from ribosomal peptide biosynthesis macrocyclizes diverse substrates, including those resembling nonribosomal peptide and hybrid polyketide-peptide products. The proposed mechanism is analogous to thioesterase-catalyzed chemistry, but the substrates are amide bonds rathe...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2010
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975588/ https://ncbi.nlm.nih.gov/pubmed/20961047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1067806 |
| Tagiau: |
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