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Circular logic: Nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst
[Image: see text] A protease from ribosomal peptide biosynthesis macrocyclizes diverse substrates, including those resembling nonribosomal peptide and hybrid polyketide-peptide products. The proposed mechanism is analogous to thioesterase-catalyzed chemistry, but the substrates are amide bonds rathe...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975588/ https://ncbi.nlm.nih.gov/pubmed/20961047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1067806 |
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