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Novel mouse model reveals that serine phosphorylation of L-plastin is essential for effective splenic clearance of pneumococcus

Asplenia imparts susceptibility to life-threatening sepsis with encapsulated bacteria, such as the pneumococcus. However, the cellular components within the splenic environment that guard against pneumococcal bacteremia have not been defined. The actin-bundling protein L-plastin (LPL) is essential f...

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Anaya, Edgar P., Lin, Xue, Todd, Elizabeth M., Szasz, Taylor P., Morley, S. Celeste
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323710/
https://ncbi.nlm.nih.gov/pubmed/33858961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000899
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