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LRRK1 regulation of actin assembly in osteoclasts involves serine 5 phosphorylation of L‐plastin
Mice with disruption of Lrrk1 and patients with nonfunctional mutant Lrrk1 exhibit severe osteopetrosis phenotypes because of osteoclast cytoskeletal dysfunction. To understand how Lrrk1 regulates osteoclast function by modulating cytoskeleton rearrangement, we examined the proteins that are differe...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Cell Biochem |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6218268/ https://ncbi.nlm.nih.gov/pubmed/30136304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.27377 |
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