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L-Plastin Is Essential for Alveolar Macrophage Production and Control of Pulmonary Pneumococcal Infection
We report that mice deficient for the hematopoietic-specific, actin-bundling protein L-plastin (LPL) succumb rapidly to intratracheal pneumococcal infection. The increased susceptibility of LPL(−/−) mice to pulmonary pneumococcal challenge correlated with reduced numbers of alveolar macrophages, con...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3993441/ https://ncbi.nlm.nih.gov/pubmed/24595139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01199-13 |
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