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Intrinsic T- and B-cell deficits impair T cell-dependent antibody responses in mice lacking the actin-bundling protein L-plastin

Germinal center development, critical for long-term humoral immunity, requires the trafficking of T and B lymphocytes to defined tissues and locations after antigenic challenge. The molecular mechanisms that support lymphocyte trafficking through the linkage of extracellular chemotactic and adhesive...

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Main Authors: Todd, Elizabeth M., Deady, Lauren E., Morley, Sharon Celeste
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794664/
https://ncbi.nlm.nih.gov/pubmed/23589339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242780
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