Alveolar macrophage development in mice requires L-plastin for cellular localization in alveoli

Alveolar macrophages are lung-resident sentinel cells that develop perinatally and protect against pulmonary infection. Molecular mechanisms controlling alveolar macrophage generation have not been fully defined. Here, we show that the actin-bundling protein L-plastin (LPL) is required for the perin...

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Bibliographic Details
Published in:Blood
Main Authors: Todd, Elizabeth M., Zhou, Julie Y., Szasz, Taylor P., Deady, Lauren E., D’Angelo, June A., Cheung, Matthew D., Kim, Alfred H. J., Morley, Sharon Celeste
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2016
Subjects:
Immunobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159703/
https://ncbi.nlm.nih.gov/pubmed/27758872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-705962
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