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Striatal GABAergic interneuron dysfunction in the Q175 mouse model of Huntington’s disease

The pathological hallmark of Huntington’s disease (HD) is the massive loss of striatal and cortical neurons. Until recently, it was believed that striatal interneurons were spared from degeneration. This view has changed after the demonstration that parvalbumin (PV)-expressing interneurons also are...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Holley, Sandra M., Galvan, Laurie, Kamdjou, Talia, Cepeda, Carlos, Levine, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320683/
https://ncbi.nlm.nih.gov/pubmed/30472747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14283
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