JFK Is a Hypoxia-Inducible Gene That Functions to Promote Breast Carcinogenesis

Many carcinomas feature hypoxia, a condition has long been associated with tumor progression and poor prognosis, as well as resistance to chemoradiotherapy. Here, we report that the F-box protein JFK promotes mammary tumor initiation and progression in MMTV-PyMT murine model of spontaneous breast ca...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Yang, Ziran, Zhou, Xuehong, Zheng, Enrun, Wang, Yizhou, Liu, Xinhua, Wang, Yue, Wang, Yanpu, Liu, Zhaofei, Pei, Fei, Zhang, Yue, Ren, Jie, Huang, Yunchao, Xia, Lu, Guan, Sudun, Qin, Sen, Suo, Feiya, Shi, Jie, Wang, Lijing, He, Lin, Sun, Luyang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319627/
https://ncbi.nlm.nih.gov/pubmed/34336836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.686737
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