High dietary potassium causes ubiquitin-dependent degradation of the kidney sodium-chloride cotransporter

The thiazide-sensitive sodium-chloride cotransporter (NCC) in the renal distal convoluted tubule (DCT) plays a critical role in regulating blood pressure (BP) and K(+) homeostasis. During hyperkalemia, reduced NCC phosphorylation and total NCC abundance facilitate downstream electrogenic K(+) secret...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Kortenoeven, Marleen L.A., Esteva-Font, Cristina, Dimke, Henrik, Poulsen, Søren B., Murali, Sathish K., Fenton, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318901/
https://ncbi.nlm.nih.gov/pubmed/34174287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100915
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares