Synthetic dysmobility screen unveils an integrated STK40-YAP-MAPK system driving cell migration

Integrating signals is essential for cell survival, leading to the concept of synthetic lethality. However, how signaling is integrated to control cell migration remains unclear. By conducting a “two-hit” screen, we revealed the synergistic reduction of cell migration when serine-threonine kinase 40...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Yu, Ling-Yea, Tseng, Ting-Jen, Lin, Hsuan-Chao, Hsu, Chi-Lin, Lu, Ting-Xuan, Tsai, Chia-Jung, Lin, Yu-Chiao, Chu, I, Peng, Chien-Tzu, Chen, Hou-Jen, Tsai, Feng-Chiao
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318371/
https://ncbi.nlm.nih.gov/pubmed/34321207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg2106
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