Synthetic dysmobility screen unveils an integrated STK40-YAP-MAPK system driving cell migration

Integrating signals is essential for cell survival, leading to the concept of synthetic lethality. However, how signaling is integrated to control cell migration remains unclear. By conducting a “two-hit” screen, we revealed the synergistic reduction of cell migration when serine-threonine kinase 40...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Adv
Auteurs principaux: Yu, Ling-Yea, Tseng, Ting-Jen, Lin, Hsuan-Chao, Hsu, Chi-Lin, Lu, Ting-Xuan, Tsai, Chia-Jung, Lin, Yu-Chiao, Chu, I, Peng, Chien-Tzu, Chen, Hou-Jen, Tsai, Feng-Chiao
Format: Artigo
Langue:Inglês
Publié: American Association for the Advancement of Science 2021
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318371/
https://ncbi.nlm.nih.gov/pubmed/34321207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg2106
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