Synthetic dysmobility screen unveils an integrated STK40-YAP-MAPK system driving cell migration

Integrating signals is essential for cell survival, leading to the concept of synthetic lethality. However, how signaling is integrated to control cell migration remains unclear. By conducting a “two-hit” screen, we revealed the synergistic reduction of cell migration when serine-threonine kinase 40...

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Detalhes bibliográficos
Publicado no:Sci Adv
Principais autores: Yu, Ling-Yea, Tseng, Ting-Jen, Lin, Hsuan-Chao, Hsu, Chi-Lin, Lu, Ting-Xuan, Tsai, Chia-Jung, Lin, Yu-Chiao, Chu, I, Peng, Chien-Tzu, Chen, Hou-Jen, Tsai, Feng-Chiao
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318371/
https://ncbi.nlm.nih.gov/pubmed/34321207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg2106
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