Targeting the VEGF-C/VEGFR3 axis suppresses Slug-mediated cancer metastasis and stemness via inhibition of KRAS/YAP1 signaling

Vascular endothelial growth factor-C (VEGF-C) has been implicated in epithelial-mesenchymal transition (EMT) processes and various human cancers, including skin cancer. Skin cancer is an aggressive human malignancy with increasing incidence worldwide; however, the underlying mechanisms involved in V...

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Опубликовано в: :Oncotarget
Главные авторы: Yeh, Yu-Wen, Cheng, Ching-Chia, Yang, Shu-Ting, Tseng, Chi-Feng, Chang, Ting-Yu, Tsai, Sin-Ying, Fu, Earl, Chiang, Chien-Ping, Liao, Li-Chuan, Tsai, Pei-Wen, Yu, Yung-Luen, Su, Jen-Liang
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Review
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354933/
https://ncbi.nlm.nih.gov/pubmed/27901498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13629
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