The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging

Multifunctional N6-methyladenosine (m6A) has been revealed to be an important epigenetic component in various physiological and pathological processes, but its role in female ovarian aging remains unclear. Thus, we demonstrated m6A demethylase FTO downregulation and the ensuing increased m6A in gran...

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Publicat a:Cell Death Dis
Autors principals: Jiang, Zhong-xin, Wang, Yi-ning, Li, Zi-yuan, Dai, Zhi-hui, He, Yi, Chu, Kun, Gu, Jia-yi, Ji, Yi-Xuan, Sun, Ning-xia, Yang, Fu, Li, Wen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316443/
https://ncbi.nlm.nih.gov/pubmed/34315853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04016-9
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