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The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging

Multifunctional N6-methyladenosine (m6A) has been revealed to be an important epigenetic component in various physiological and pathological processes, but its role in female ovarian aging remains unclear. Thus, we demonstrated m6A demethylase FTO downregulation and the ensuing increased m6A in gran...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Jiang, Zhong-xin, Wang, Yi-ning, Li, Zi-yuan, Dai, Zhi-hui, He, Yi, Chu, Kun, Gu, Jia-yi, Ji, Yi-Xuan, Sun, Ning-xia, Yang, Fu, Li, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316443/
https://ncbi.nlm.nih.gov/pubmed/34315853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04016-9
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