The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging

Multifunctional N6-methyladenosine (m6A) has been revealed to be an important epigenetic component in various physiological and pathological processes, but its role in female ovarian aging remains unclear. Thus, we demonstrated m6A demethylase FTO downregulation and the ensuing increased m6A in gran...

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Vydáno v:Cell Death Dis
Hlavní autoři: Jiang, Zhong-xin, Wang, Yi-ning, Li, Zi-yuan, Dai, Zhi-hui, He, Yi, Chu, Kun, Gu, Jia-yi, Ji, Yi-Xuan, Sun, Ning-xia, Yang, Fu, Li, Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316443/
https://ncbi.nlm.nih.gov/pubmed/34315853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04016-9
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