Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy

Germline alterations in the RB1 tumor suppressor gene predispose patients to develop retinoblastoma (RB) in both eyes. While similar treatment is given for each eye, there is often a variable therapeutic response between the eyes. Herein, we use the aqueous humor (AH) liquid biopsy to evaluate the c...

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Bibliografiske detaljer
Udgivet i:NPJ Precis Oncol
Main Authors: Wong, Elyssa Y., Xu, Liya, Shen, Lishuang, Kim, Mary E., Polski, Ashley, Prabakar, Rishvanth K., Shah, Rachana, Jubran, Rima, Kim, Jonathan W., Biegel, Jaclyn A., Gai, Xiaowu, Kuhn, Peter, Hicks, James, Berry, Jesse L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316348/
https://ncbi.nlm.nih.gov/pubmed/34316014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00212-0
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