Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy

Germline alterations in the RB1 tumor suppressor gene predispose patients to develop retinoblastoma (RB) in both eyes. While similar treatment is given for each eye, there is often a variable therapeutic response between the eyes. Herein, we use the aqueous humor (AH) liquid biopsy to evaluate the c...

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Detalhes bibliográficos
Publicado no:NPJ Precis Oncol
Main Authors: Wong, Elyssa Y., Xu, Liya, Shen, Lishuang, Kim, Mary E., Polski, Ashley, Prabakar, Rishvanth K., Shah, Rachana, Jubran, Rima, Kim, Jonathan W., Biegel, Jaclyn A., Gai, Xiaowu, Kuhn, Peter, Hicks, James, Berry, Jesse L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316348/
https://ncbi.nlm.nih.gov/pubmed/34316014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00212-0
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