Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy

Germline alterations in the RB1 tumor suppressor gene predispose patients to develop retinoblastoma (RB) in both eyes. While similar treatment is given for each eye, there is often a variable therapeutic response between the eyes. Herein, we use the aqueous humor (AH) liquid biopsy to evaluate the c...

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Detalles Bibliográficos
Publicado en:NPJ Precis Oncol
Autores principales: Wong, Elyssa Y., Xu, Liya, Shen, Lishuang, Kim, Mary E., Polski, Ashley, Prabakar, Rishvanth K., Shah, Rachana, Jubran, Rima, Kim, Jonathan W., Biegel, Jaclyn A., Gai, Xiaowu, Kuhn, Peter, Hicks, James, Berry, Jesse L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
Materias:
Case Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316348/
https://ncbi.nlm.nih.gov/pubmed/34316014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00212-0
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