The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite

The emergence and spread of Plasmodium falciparum parasites resistant to front-line antimalarial artemisinin-combination therapies (ACT) threatens to erase the considerable gains against the disease of the last decade. Here, we develop a large-scale phenotypic screening pipeline and use it to carry...

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Udgivet i:Nat Commun
Main Authors: Zhang, Min, Wang, Chengqi, Oberstaller, Jenna, Thomas, Phaedra, Otto, Thomas D., Casandra, Debora, Boyapalle, Sandhya, Adapa, Swamy R., Xu, Shulin, Button-Simons, Katrina, Mayho, Matthew, Rayner, Julian C., Ferdig, Michael T., Jiang, Rays H. Y., Adams, John H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316339/
https://ncbi.nlm.nih.gov/pubmed/34315897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24814-1
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