Altered expression of K13 disrupts DNA replication and repair in Plasmodium falciparum

BACKGROUND: Plasmodium falciparum exhibits resistance to the artemisinin component of the frontline antimalarial treatment Artemisinin-based Combination Therapy in South East Asia. Millions of lives will be at risk if artemisinin resistance (ART-R) spreads to Africa. Single non-synonymous mutations...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Gibbons, Justin, Button-Simons, Katrina A., Adapa, Swamy R., Li, Suzanne, Pietsch, Maxwell, Zhang, Min, Liao, Xiangyun, Adams, John H., Ferdig, Michael T., Jiang, Rays H. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263542/
https://ncbi.nlm.nih.gov/pubmed/30486796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5207-7
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