Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery

The spread of Plasmodium falciparum multidrug resistance highlights the urgency to discover new targets and chemical scaffolds. Unfortunately, lack of experimentally validated functional information about most P. falciparum genes remains a strategic hurdle. Chemogenomic profiling is an established t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pradhan, Anupam, Siwo, Geoffrey H., Singh, Naresh, Martens, Brian, Balu, Bharath, Button-Simons, Katrina A., Tan, Asako, Zhang, Min, Udenze, Kenneth O., Jiang, Rays H.Y., Ferdig, Michael T., Adams, John H., Kyle, Dennis E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635350/
https://ncbi.nlm.nih.gov/pubmed/26541648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15930
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