Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery

The spread of Plasmodium falciparum multidrug resistance highlights the urgency to discover new targets and chemical scaffolds. Unfortunately, lack of experimentally validated functional information about most P. falciparum genes remains a strategic hurdle. Chemogenomic profiling is an established t...

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Udgivet i:Sci Rep
Main Authors: Pradhan, Anupam, Siwo, Geoffrey H., Singh, Naresh, Martens, Brian, Balu, Bharath, Button-Simons, Katrina A., Tan, Asako, Zhang, Min, Udenze, Kenneth O., Jiang, Rays H.Y., Ferdig, Michael T., Adams, John H., Kyle, Dennis E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635350/
https://ncbi.nlm.nih.gov/pubmed/26541648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15930
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