Punctuated chromatin states regulate Plasmodium falciparum antigenic variation at the intron and 2 kb upstream regions

BACKGROUND: Understanding the regulation mechanism of var gene expression is crucial for explaining antigenic variation in Plasmodium falciparum. Recent work observed that while all var genes produce transcripts, only a few var genes exhibit high expression levels. However, the global regulation of...

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Publicado en:BMC Genomics
Autores principales: Wang, Chengqi, Adapa, Swamy R., Gibbons, Justin, Sutton, Stephen, Jiang, Rays H. Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990864/
https://ncbi.nlm.nih.gov/pubmed/27538502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3005-7
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