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Role of Synonymous Mutations in the Evolution of TEM β-Lactamase Genes
Nonsynonymous mutations are well documented in TEM β-lactamases. The resulting amino acid changes often alter the conferred phenotype from broad spectrum (2b) conferred by TEM-1 to extended spectrum (2be), inhibitor resistant (2br), or both extended spectrum and inhibitor resistant (2ber). The encod...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8315918/ https://ncbi.nlm.nih.gov/pubmed/33820762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00018-21 |
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