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Protocol to apply spike-in ChIP-seq to capture massive histone acetylation in human cells

Inhibition of histone deacetylases causes rapid and robust acetylation of histones. In this case, histone acetylation is likely increased on nearly every nucleosome, and the per-cell DNA/chromatin yield in chromatin immunoprecipitation (ChIP) experiments is significantly increased. Spike-in controls...

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Podrobná bibliografie
Vydáno v:STAR Protoc
Hlavní autoři: Wu, Di, Wang, Liguo, Huang, Haojie
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313745/
https://ncbi.nlm.nih.gov/pubmed/34337446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100681
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