α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice

Inflammation and extracellular matrix (ECM) degradation have been implicated in the pathological process of osteoarthritis (OA). α-Cyperone is the main active component of the traditional Chinese medicine Cyperus rotundus L. In this study, we found that α-Cyperone abolished the IL-1β-induced product...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhang, Huawei, Li, Sunlong, Lu, Jiajie, Jin, Jie, Zhu, Gaosheng, Wang, Libo, Yan, Yingzhao, He, Linjie, Wang, Ben, Wang, Xiangyang, Yu, Huachen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312409/
https://ncbi.nlm.nih.gov/pubmed/34237707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203259
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados