Schisandrin B ameliorated chondrocytes inflammation and osteoarthritis via suppression of NF-κB and MAPK signal pathways

INTRODUCTION: Osteoarthritis (OA) is the most prevalent joint disorder in the elderly population, and inflammatory mediators like IL-1β were thought to play central roles in its development. Schisandrin B, the main active component derived from Schisandra chinensis, exhibited anti-oxidative and anti...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Ran, Jisheng, Ma, Chiyuan, Xu, Kai, Xu, Langhai, He, Yuzhe, Moqbel, Safwat Adel Abdo, Hu, Pengfei, Jiang, Lifeng, Chen, Weiping, Bao, Jiapeng, Xiong, Yan, Wu, Lidong
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953308/
https://ncbi.nlm.nih.gov/pubmed/29785089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S162014
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