Schisandrin B ameliorated chondrocytes inflammation and osteoarthritis via suppression of NF-κB and MAPK signal pathways

INTRODUCTION: Osteoarthritis (OA) is the most prevalent joint disorder in the elderly population, and inflammatory mediators like IL-1β were thought to play central roles in its development. Schisandrin B, the main active component derived from Schisandra chinensis, exhibited anti-oxidative and anti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Des Devel Ther
Prif Awduron: Ran, Jisheng, Ma, Chiyuan, Xu, Kai, Xu, Langhai, He, Yuzhe, Moqbel, Safwat Adel Abdo, Hu, Pengfei, Jiang, Lifeng, Chen, Weiping, Bao, Jiapeng, Xiong, Yan, Wu, Lidong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2018
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953308/
https://ncbi.nlm.nih.gov/pubmed/29785089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S162014
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