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A Genetically Encoded Fluorosulfonyloxybenzoyl-L-lysine for Expansive Covalent Bonding of Proteins via SuFEx Chemistry

Genetically introducing novel chemical bonds into proteins provides innovative avenues for biochemical research, protein engineering, and biotherapeutic applications. Recently, latent bioreactive unnatural amino acids (Uaas) have been incorporated into proteins to covalently target natural residues...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Liu, Jun, Cao, Li, Klauser, Paul C., Cheng, Rujin, Berdan, Viktoriya Y., Sun, Wei, Wang, Nanxi, Ghelichkhani, Farid, Yu, Bingchen, Rozovsky, Sharon, Wang, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310613/
https://ncbi.nlm.nih.gov/pubmed/34213894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c04259
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