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SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
Sulfur(VI) Fluoride Exchange (SuFEx) is a new family of click chemistry transformations which relies on readily available materials to produce compounds bearing the SVI—F motif. The potential of SuFEx in drug discovery has just started to be explored. We report the first method of SuFEx chemistry fo...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192542/ https://ncbi.nlm.nih.gov/pubmed/29451783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b12788 |
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